Anakinra’s effectiveness in pericarditis: A systematic review

Anakinra's effectiveness in pericarditis: A systematic review

Patient outcomes significantly improved as a result of anakinra. In addition, compared to conventional care, the pericarditis recovered more quickly and had a decreased risk of recurrence. Pericarditis, an inflammation of the pericardium, can cause severe chest pain and is likely to return despite therapy. An infection of the digestive or respiratory systems, pericarditis, can develop. Autoimmune conditions like lupus, scleroderma and rheumatoid arthritis can lead to chronic and recurrent pericarditis. When it comes to anakinra cost in India, you will get it at an affordable price. If you have constrictive pericarditis, your doctor might advise a low-salt diet. Avoid sweets, alcohol, and saturated fats since these can exacerbate inflammation and impair your immune system.

In this post, you can see the systematic review of anakinra’s effectiveness in pericarditis:

About anakinra

In adults and children, anakinra is used to treat interleukin-1 receptor antagonist deficiency, a condition in which the body attacks its tissues, causing inflammation and affecting the bones, nervous system, skin, lungs, liver, and joints. Interleukin antagonists, which include Anakinra, are a class of drugs.

Anakinra is sold under the name of Kineret. Anakinra injection prices in India are low compared to other countries. An IL-1 receptor monoclonal antibody or IL-1 receptor antagonist is anakinra.

Introduction and background

The double-layered membrane that encircles the heart is called the pericardium. Pericarditis, which accounts for 5% of emergency room visits for chest pain, is the thickening and inflammation of this membrane. Even with treatment, the recurrence rate can reach 24%. Idiopathic causes include coxsackie A and B, echovirus, adenovirus, human immunodeficiency virus are thought to be the most frequent causes of pericarditis. Anakinra cost in India is reasonable to buy so that people can buy it easily.

Autoimmune inflammatory diseases like hypothyroidism, Wegner’s granulomatosis, systemic lupus erythematosus, scleroderma, inflammatory bowel disease, and rheumatoid arthritis are also causes. Medications like doxorubicin, isoniazid, phenytoin, and procainamide have also been linked to pericardial inflammation. Contrary to other causes, pericarditis brought on by drugs typically goes away as the offending substance is stopped.


The 2015 guidelines state that the presence of two of the following four signs pericardial chest pain, the classic auscultation sound of a triphasic scratchy friction rub, PR depression or diffuse ST elevation on the electrocardiogram, and pericardial effusion on imaging tests like echocardiography, CT, or MRI confirms the presence of pericarditis. It is advisable to have treatment from an Indian hospital because anakinra injection prices in India are low.


Steroids, colchicine, and nonsteroidal anti-inflammatory medications, including aspirin and ibuprofen, are all commonly used to treat pericarditis. Pericardiocentesis, or the formation of a pleuropericardial window, can be used to treat pericarditis aggravated by tamponade. It is a serious issue with the current treatments that one in four patients will experience a recurrence during the first few weeks. The monoclonal antibodies anakinra, canakinumab, and rilonacept are among the medications now being studied to improve the treatment plans already in use.

Wrapping it up

As a result, the above details are about the systematic review of anakinra’s effectiveness in pericarditis. If the patient suffers from pericarditis, you can treat them with the anakinra, which will mostly react with all human body types.

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